Overview

Tadagra is a brand that contains tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor. It helps relax blood vessels in specific tissues, supporting better circulation when sexually stimulated.

Active ingredient
Tadalafil
Conditions addressed
Erectile dysfunction (ED); symptoms of benign prostatic hyperplasia (BPH). It can also influence blood pressure because it vasodilates blood vessels.
Available strength noted on this page
20 mg

For faster navigation, jump to dosage, interactions, or U.S. legal notes.

Medical disclaimer: This page is informational and does not replace advice from your own clinician.

What it is used for

Tadagra (tadalafil) is taken by adult men for:

  • Erectile dysfunction: improves erectile response with sexual stimulation.
  • BPH symptoms: may reduce urinary hesitancy, weak stream, and frequency related to enlarged prostate.

It does not create sexual desire by itself; stimulation is still required. For tips on safe use and scheduling, see How to take it.

How to take it

Always follow your prescriber's instructions. Swallow tablets whole with water. Try to take it at roughly the same time if you are on a daily regimen.

Typical approaches your clinician may consider:

  • On-demand for ED: 10 to 20 mg taken about 30 to 60 minutes before sexual activity; do not exceed once daily.
  • Once-daily dosing: commonly 2.5 to 5 mg for men who prefer chronic use or for BPH; your clinician may adjust based on response and tolerability.

This page focuses on the 20 mg strength listed above. Food does not meaningfully change onset, but heavy or very fatty meals may slow effects slightly. Avoid excessive alcohol, which can increase dizziness and lower blood pressure.

If you have questions about splitting or changing strengths, ask your pharmacist. For safety warnings about co-medications, see Drug and food interactions.

Precautions

Before starting tadalafil, tell your clinician if any of the following apply:

  • History of cardiovascular disease, chest pain with exertion or sex, arrhythmias, or heart failure.
  • Kidney or liver impairment.
  • Penile anatomical deformities or conditions that predispose to priapism.
  • Sudden changes in vision or hearing, or a history of those problems.
  • Low baseline blood pressure or episodes of fainting.

Seek urgent care if you develop chest pain during sexual activity, if vision or hearing changes suddenly, or if an erection persists beyond 4 hours (priapism). For absolute reasons not to use this medicine, see Do not use if.

Do not use if

Do not take Tadagra (tadalafil) if any of the following are true:

  • You use any nitrate medicines (for example, nitroglycerin) or amyl nitrite. Serious, potentially dangerous drops in blood pressure can occur.
  • You take riociguat for pulmonary arterial hypertension.
  • Allergy to tadalafil or any tablet component.
  • Unstable cardiovascular disease, recent heart attack within 90 days, or stroke within 6 months.
  • Severe liver disease or marked hypotension.
  • Hereditary eye disorders such as retinitis pigmentosa.

This product is not intended for women or for anyone under 18 years of age. If you are uncertain whether a condition applies to you, review the interactions and speak with your prescriber.

Possible side effects

Many effects are mild and short-lived. Contact a clinician if they are severe or persistent.

  • Nasal congestion
  • Headache
  • Back pain
  • Dizziness
  • Indigestion or stomach upset

Less common: flushing, muscle aches, or visual color tinge. Stop use and seek urgent care for chest pain, sudden vision or hearing loss, or erections lasting more than 4 hours.

Drug and food interactions

Always provide your clinician and pharmacist a full list of prescription drugs, OTC medicines, vitamins, and herbal supplements before starting tadalafil.

  • Nitrates or amyl nitrite: absolutely contraindicated due to profound blood pressure drop.
  • Riociguat: do not combine.
  • Alpha blockers and antihypertensives: additive blood pressure lowering may occur; dose separation and monitoring may be required.
  • Strong CYP3A4 inhibitors (for example, ketoconazole, itraconazole, clarithromycin, ritonavir): can raise tadalafil levels; dose adjustment or avoidance may be needed.
  • CYP3A4 inducers (for example, rifampin, carbamazepine, phenytoin): may reduce effectiveness.
  • Alcohol: increases dizziness and orthostatic hypotension; use modest amounts if at all.
  • Grapefruit or grapefruit juice: may increase tadalafil levels; discuss with your clinician.

If you have a surgery or procedure scheduled, inform your care team you use tadalafil.

Missed dose

Daily regimen: take the missed dose when remembered if the next dose is not due soon. Skip it if it is almost time for the next dose. Do not double up.

On-demand regimen: you take a dose only before sexual activity, so there is no scheduled dose to make up.

Overdose

Too much tadalafil can cause severe dizziness, fainting, or prolonged erection. Call your clinician, go to the nearest emergency department, or contact Poison Control in the U.S. at 1-800-222-1222. If symptoms are severe, call 911 immediately.

Storage

Keep tablets in the original blister or bottle at room temperature, protected from heat, moisture, and direct light. Store out of reach of children and pets. Do not use past the expiration date.

Alternatives and similar medicines

If tadalafil is not suitable or available, clinicians may consider other FDA-approved options with similar goals. Discuss these choices and your medical history to choose an appropriate therapy.

  • Sildenafil (Viagra and generics): shorter duration; often taken 30-60 minutes before activity.
  • Vardenafil (Levitra, Staxyn generics): comparable onset to sildenafil; orally disintegrating forms exist.
  • Avanafil (Stendra): quicker onset for some users; may be taken closer to activity.
  • Daily tadalafil 2.5-5 mg (FDA-approved): for men needing frequent dosing or for BPH symptoms.
  • For BPH without ED: tamsulosin, alfuzosin, or finasteride/dutasteride may be considered as non-PDE5 options.
  • Non-drug alternatives: vacuum erection devices, psychosexual therapy, lifestyle changes, and management of cardiovascular risk factors.

Note: Tadagra as a brand may not be FDA-approved in the USA. U.S. pharmacies dispense FDA-approved tadalafil generics and brands. For legal details, jump to U.S. legal and regulatory notes.

Typical prices in USD

Prices vary by pharmacy, insurance, discount programs, and strength. Approximate out-of-pocket U.S. retail prices per tablet:

  • FDA-approved generic tadalafil 20 mg: about $0.50 to $4.00 per tablet with common discount cards; $5 to $15 without discounts at some pharmacies.
  • Brand Cialis 20 mg: roughly $15 to $70 per tablet depending on pharmacy and quantity.
  • Other PDE5 inhibitors:
    • Sildenafil 50-100 mg generics: about $0.20 to $2.00 per tablet with discounts; $5 to $15 brand Viagra.
    • Vardenafil generics: about $1 to $5 per tablet; brand typically higher.
    • Avanafil (Stendra): often $10 to $40 per tablet.

These price ranges are rough estimates and can change. Check local pharmacies or legitimate U.S. online pharmacies for current pricing.